Denosumab: 6 Monthly Injections for the Treatment of Osteoporosis - Rheumatology Consultant London | Rheumatologist London | Dr Stephanie Barrett



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There are a wide range of different treatments of osteoporosis and six monthly injections are a common option. These injections are of the drug treatment denosumab which helps to reduce the risk of bones breaking when you have osteoporosis.

What is Osteoporosis?

Osteoporosis is a condition which sees the ‘struts’ which make up the structure within our bones become thin and weakened and therefore break more easily. The wrists, hips and spine are most commonly affected by osteoporosis, although it can occur in any bone.

What is Denosumab?

Denosumab comes in six monthly injection form for the treatment of osteoporosis. It is a drug treatment is administered as a sub-cutaneous injection and can be given in hospital, at a specific clinic or sometimes by GPs. It will help strengthen your bones. There will be no pain relief and will not have any impact on the pain that comes with broken bones. Your bones will become stronger with this treatment and it can reduce the risk of fractures.

Denosumab is a monoclonal antibody which inhibits the cells which break bones down. This means it can prevent bone loss.

Is Denosumab suitable for your condition?

Sometimes denosumab is not a suitable treatment of osteoporosis. In the below circumstances the treatment will not be offered:

  • If you have hypocalcaemia – a low blood calcium level
  • If you have a rare intolerance of fructose
  • People with a latex allergy
  • Anybody pregnant or breastfeeding

Remember, this treatment of osteoporosis wears off quite quickly once the six month point comes around. Sticking regularly to the rejections is the best way to avoid any unnecessary risk and continue to strengthen your bones against the condition. Osteoporosis treatment comes in many forms, but these six monthly injections are becoming more popular. It is not right for everyone but it is something you can discuss with your specialist.